Snouthead Nefarious is a mad scientist specializing in genetics. He is a hateful jerk and part-time supervillain, with a violent temper and weakness for hookers and blow. He makes crazy potions and makes them into mutation bombs, which alter victims into animal hybrids. His aim is to mutate the world. He can snort any substance into his snout and blast it back at his enemies.
His favorite creation-slash-henchwoman (and possibly more??) is MC Lady Birdbeast, a freak with bear and bird DNA. She is an aspiring rapper, and Snouthead finds himself thrown into the role of her mananger.